Blog Post Title: Stocks Update for August 17, 2023: Nanox, Immatics, Selecta Biosciences, NuCana, and Twin Disc

Introduction:

NANO-X IMAGING LTD Reports Progress towards Global Supply Chain Development

NANO-X IMAGING LTD, an innovative medical imaging technology company, recently released its second-quarter results and provided a business update. The company ended the second quarter of 2023 with $80.3 million in cash, cash equivalents, restricted cash, and marketable securities.

One significant highlight of the quarter was the 510(k) clearance received from the U.S. Food and Drug Administration (FDA) on April 28, 2023. This clearance allows Nanox to market the Nanox.ARC, a stationary X-ray system designed to produce tomographic images of the human musculoskeletal system.

In terms of financials, Nanox generated $2.6 million in revenue during the second quarter of 2023, compared to $2.2 million in the same quarter last year. This positive revenue growth indicates a promising trend for the company’s financial performance.

Additionally, Nanox made progress in securing future supplies of chips and tubes through multiple partnership agreements. This strategic move ensures a stable supply chain, reducing the risk of manufacturing delays and enhancing the company’s ability to meet customer demand.

Furthermore, Nanox entered into an Original Equipment Manufacturing Collaboration with a U.S. government agency. This collaboration aims to develop security scanning and testing applications, highlighting the company’s expanding footprint within the medical imaging industry.

Nanox is also working tirelessly to deploy its first Nanox.ARC system in a clinical setting in an East Coast facility in the United States. With the clearance and import license obtained, the system has arrived in the U.S., paving the way for its utilization in a real-world medical environment.

As a long-term investor, I am pleased with the progress Nanox has made in expanding its global supply chain and securing key partnerships. These efforts will undoubtedly contribute to the company’s growth and market presence. With the positive revenue growth and the potential for further expansion with strategic collaborations, I recommend considering buying or holding onto NANO-X IMAGING LTD stocks.

Overall, NANO-X IMAGING LTD’s second quarter of 2023 showcased significant achievements in product clearance, revenue growth, supply chain development, and strategic collaborations. This combination of positive developments positions the company well for future success and warrants a positive outlook for its stock performance.

Immatics Reports Positive Interim Clinical Data for TCER® IMA402 Targeting PRAMEACTengine® IMA203 TCR-T Therapy

Immatics N.V., a leading clinical-stage biopharmaceutical company specializing in T cell-redirecting cancer immunotherapies, released encouraging interim clinical data for their second next-generation half-life extended TCR Bispecific program, TCER® IMA402. The phase 1/2 clinical trial evaluated the efficacy of IMA402 targeting PRAMEACTengine® IMA203 TCR-T monotherapy against PRAME.

In the interim clinical update, 11 heavily pre-treated patients in Phase 1b showed a remarkable 67% confirmed objective response rate (ORR). The median duration of response was not reached at a median follow-up time of 8.5 months at data cut-off. These results demonstrate the potential of IMA402 as an effective treatment for solid cancer indications.

As an investor, I am thrilled by this positive news from Immatics. The encouraging initial outcomes, durable responses, and indication of fast-tracking IMA203 for high-need solid cancers are all promising factors. This development positions Immatics as a potential leader in the field of cancer immunotherapies.

In addition to the clinical update, Immatics also announced that Bristol Myers Squibb has exercised their first opt-in into the cell therapy collaboration initiated in 2019. This not only strengthens the partnership but also brings in a $15 million option fee and a $35 million equity investment. Furthermore, Immatics disclosed that their cash and cash equivalents, excluding the recent investment, amount to $377.7 million1 (€347.6) as of June 30, 2023, extending the projected cash runway to late 2025.

Overall, the positive interim clinical data and the strong financial position of Immatics make this an opportune moment for investors. Considering the remarkable efficacy demonstrated in this trial, I highly recommend buying Immatics stock to capitalize on the potential future success of their TCR Bispecific program, TCER® IMA402.

Selecta Biosciences Reports Financial Results and Provides Business Update

Selecta Biosciences, a biotechnology company, announced its focus on advancing SEL-212, a potential treatment for chronic refractory gout. The company is on track for the Biologics License Application (BLA) filing in the first half of 2024. However, in a bid to maximize stockholder value, Selecta plans to suspend further investment in the majority of its pipeline assets and instead explore potential licensing and corporate development initiatives. This strategic decision aims to extend the company’s cash runway into 2027.

Carsten Brunn, President and CEO of Selecta Biosciences, expressed their commitment to SEL-212, which has the potential to generate over $700 million in peak sales in the U.S. The company believes in preserving capital and maintaining stockholders’ interests without dilution.

Considering this update, it is advisable to hold the stock as the company’s focus on advancing SEL-212 suggests confidence in its potential success. The decision to maximize stockholder value demonstrates a strategic approach. With the impending BLA filing and positive outlook for SEL-212, there are promising prospects for the company.

NuCana plc Announces Financial Results and Updates on Clinical Development Program

NuCana plc, a pharmaceutical company based in the United Kingdom, recently released its financial results for the second quarter ended June 30, 2023, along with an update on its clinical development program featuring its ProTide therapeutics.

As of June 30, 2023, NuCana reported cash and cash equivalents of £24.6 million, indicating a decrease from the previous quarter. Despite the decrease, the company remains well-capitalized with anticipated cash runway extending into 2025. NuCana’s net loss for the quarter was £5.4 million, slightly higher compared to the same period last year.

NuCana’s primary focus for the first half of 2023 was advancing their ProTides through clinical development. The company plans to present data updates from all ongoing clinical studies in the second half of this year. Of particular interest are the three ongoing studies of their ProTide, NUC-3373. This ProTide has the potential to replace 5-FU in various tumor types. The studies include evaluating NUC-3373 combined with leucovorin and either irinotecan or oxaliplatin plus bevacizumab in second-line patients with colorectal cancer. Additionally, they are conducting a randomized Phase 2 study comparing NUFIRI plus bevacizumab to the standard of care FOLFIRI plus bevacizumab in patients with second-line colorectal cancer. Finally, they are conducting a Phase 1b/2 study of NUC-3373 in combination with pembrolizumab in solid tumor patients and in combination with docetaxel in lung cancer patients.

As a shareholder, it is encouraging to see NuCana’s commitment to advancing their ProTide therapeutics. The upcoming data updates in the second half of this year provide an opportunity for positive developments. However, it is important to monitor the progress of these studies closely, as any negative outcomes could impact the stock value. For now, I would recommend holding onto the stock and keeping a close eye on NuCana’s future updates.

Twin Disc Reports Strong Sales Growth and Improved Cash Flow in Fiscal 2023

Twin Disc, Inc. (NASDAQ: TWIN), a leading manufacturer of marine and heavy-duty industrial power transmission equipment, recently announced its financial results for the fourth quarter and full fiscal year 2023. The company reported a 10.5% year-over-year increase in sales for the fourth quarter, totaling $83.9 million. Net income attributable to Twin Disc was $8.6 million, with EBITDA reaching $13.0 million. Additionally, the company achieved a significantly improved operating cash flow of $16.0 million and a positive free cash flow of $14.9 million, compared to a negative free cash flow of $(3.4) million in the previous year.

According to John H. Batten, President and CEO of Twin Disc, fiscal 2023 was a year of two halves for the company. After experiencing supply chain disruptions and rising costs in the first half, the team successfully navigated these challenges and managed to streamline shipments and catch up on past-due orders. This, combined with pricing actions and improving supply chain conditions, contributed to the growth in sales, gross margin, and cash flow.

The company reported solid year-over-year sales growth across all product groups, indicating strong global demand. In addition, several previously canceled projects were reactivated, demonstrating positive signs of recovery from the impact of the COVID-19 pandemic. While the macroeconomic and geopolitical environment remains uncertain, Twin Disc remains cautiously optimistic due to positive project visibility, customer inquiries, and ongoing aftermarket demand.

Considering the strong financial performance and positive outlook, it is recommended to consider buying Twin Disc stock. The company’s ability to overcome challenges and achieve significant improvements in cash flow and profitability indicates a solid foundation for future growth. With the ongoing demand for its products and the commitment to delivering value to stakeholders, Twin Disc is well-positioned to continue its upward trajectory in fiscal 2024.

Investors should closely monitor Twin Disc’s performance in the coming quarters to ensure that progress remains consistent. Any signs of supply chain disruptions or declining demand could warrant reconsidering the investment. However, based on the current press release, Twin Disc appears to have successfully navigated challenges and positioned itself for continued success in the future.